{"type":"standard","title":"Spi-1 (PU.1) 5′ UTR regulatory element","displaytitle":"Spi-1 (PU.1) 5′ UTR regulatory element","namespace":{"id":0,"text":""},"wikibase_item":"Q7576852","titles":{"canonical":"Spi-1_(PU.1)_5′_UTR_regulatory_element","normalized":"Spi-1 (PU.1) 5′ UTR regulatory element","display":"Spi-1 (PU.1) 5′ UTR regulatory element"},"pageid":11422259,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/8/86/RF00232.jpg/330px-RF00232.jpg","width":320,"height":320},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/8/86/RF00232.jpg","width":452,"height":452},"lang":"en","dir":"ltr","revision":"1154722614","tid":"ff0cf1a4-f228-11ed-85e7-495e963679e8","timestamp":"2023-05-14T07:29:01Z","description":"RNA element in Spi-1 mRNA","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element","revisions":"https://en.wikipedia.org/wiki/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element?action=history","edit":"https://en.wikipedia.org/wiki/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element","edit":"https://en.m.wikipedia.org/wiki/Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Spi-1_(PU.1)_5%E2%80%B2_UTR_regulatory_element"}},"extract":"The Spi-1 (PU.1) 5′ UTR regulatory element is an RNA element found in the 5′ UTR of Spi-1 mRNA which is able to inhibit the translation Spi-1 transcripts by 8-fold. Spi-1 regulates myeloid gene expression during haemopoietic development. Mutations in this regulatory region of the 5′ UTR can lead to overexpression of Spi-1 which has been linked to development of leukaemia.","extract_html":"
The Spi-1 (PU.1) 5′ UTR regulatory element is an RNA element found in the 5′ UTR of Spi-1 mRNA which is able to inhibit the translation Spi-1 transcripts by 8-fold. Spi-1 regulates myeloid gene expression during haemopoietic development. Mutations in this regulatory region of the 5′ UTR can lead to overexpression of Spi-1 which has been linked to development of leukaemia.
"}{"slip": { "id": 200, "advice": "Sarcasm is the lowest form of wit. Employ correctly with apt timing."}}
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{"fact":"The term \u201cpuss\u201d is the root of the principal word for \u201ccat\u201d in the Romanian term pisica and the root of secondary words in Lithuanian (puz) and Low German\u00a0puus. Some scholars suggest that \u201cpuss\u201d could be imitative of the hissing sound used to get a cat\u2019s attention. As a slang word for the female pudenda, it could be associated with the connotation of a cat being soft, warm, and fuzzy.","length":387}
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